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一支由拉兹洛·安东诺夫领导的训练有素的罪犯组成的小部队在英吉利海峡深处劫持了“欧洲之星”。。农村青年楚亚军（孙淳饰）爱上了厂长王晓虹（常远饰），为了能够成为配得上她的男人，楚亚军来到了大城市打工。在一场意外中，楚亚军为了救一个孩子而被下落的电梯砸伤，成为了植物人，这让王晓虹感到非常的心碎。 王晓虹苦苦哀求著名外科医生徐志鸿，希望他能够唤醒楚亚军，于心不忍的徐志鸿决定在楚亚军的身上进行大脑移植手术。公司总经理戴璐在新婚之夜因为心脏病突发不幸丧生，而他的各项生理指标都和楚亚军完全匹配，他是最完美的脑捐献者。在经历了惊险的手术之后，楚亚军苏醒了，可是醒来的他却仿佛换了一个人一般，继承了戴璐的性格和记忆。。* Based on the manga by Inoue Noriyoshi, which has also had a SNES game spin-off. Natsume Kiroemon is the 45th leader of the Natsume family to inherit the Kouryuu no Mimi, a tool which gives its bearer easy access to wealth and women. As a result of his father's death, he leaves the Italian monastery where he had been training and to rightfully take on the name Natsume Kiroemon...。